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David H Sherman Selected Research

curacin A

7/2006Metabolic coupling of dehydration and decarboxylation in the curacin A pathway: functional identification of a mechanistically diverse enzyme pair.
8/2004Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula.

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David H Sherman Research Topics

Disease

7Neoplasms (Cancer)
01/2020 - 08/2004
3Anthrax
05/2012 - 03/2007
2Dehydration (Water Stress)
12/2016 - 07/2006
1Hypertrophy
01/2019
1Cardiomegaly (Heart Hypertrophy)
01/2019
1Colonic Neoplasms (Colon Cancer)
01/2018
1Bacterial Infections (Bacterial Infection)
11/2017
1Mouth Neoplasms (Oral Cancer)
11/2015
1Huntington Disease (Huntington's Disease)
04/2014
1Neurodegenerative Diseases (Neurodegenerative Disease)
04/2014
1Mycoses (Diseases, Fungus)
01/2013
1Shock
07/2009
1Cysts
02/2008
1Starvation
01/2008

Drug/Important Bio-Agent (IBA)

3Pharmaceutical PreparationsIBA
01/2020 - 09/2011
3Proteins (Proteins, Gene)FDA Link
01/2019 - 07/2009
3petrobactinIBA
05/2012 - 03/2007
3SiderophoresIBA
05/2012 - 03/2007
2DepsipeptidesIBA
01/2020 - 09/2011
2IronIBA
11/2017 - 03/2007
2Anti-Bacterial Agents (Antibiotics)IBA
11/2017 - 07/2009
2PolyketidesIBA
12/2016 - 10/2006
2curacin AIBA
07/2006 - 08/2004
1malbrancheamideIBA
01/2019
1Biological ProductsIBA
01/2019
1CalciumIBA
01/2019
1Calmodulin (Calcium-Dependent Activator Protein)IBA
01/2019
1Cysteine (L-Cysteine)FDA Link
01/2018
1Tryptophan (L-Tryptophan)FDA Link
01/2018
1nicoyamycin AIBA
11/2017
1Alkenes (Olefins)IBA
12/2016
1Hydro-Lyases (Dehydratases)IBA
12/2016
1Peptide Initiation Factors (Initiation Factor)IBA
11/2015
1borrelidinIBA
11/2015
1glucose-regulated proteinsIBA
11/2015
1polyglutamineIBA
04/2014
1Antiviral Agents (Antivirals)IBA
01/2013
1catechol (pyrocatechol)IBA
05/2012
1AcidsIBA
07/2009
1Sodium-Hydrogen ExchangersIBA
07/2009
1thiobutacinIBA
02/2008
1Sulfates (Sulfates, Inorganic)IBA
01/2008
1Phosphates (Orthophosphate)IBA
01/2008
1NitrogenIBA
01/2008
1Mitomycin (Mitomycin-C)FDA LinkGeneric
05/2007
1EnzymesIBA
07/2006

Therapy/Procedure

3Therapeutics
05/2007 - 10/2006